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 When I was a first-year 
            graduate student (some time ago), I had the opprotunity to learn how 
            to use a slide maker and proceeded to develop a brief seminar for 
            friends about FuPoBs (Fundamental Principles of Biology). At the time, 
            I was (mistakenly?) under the impression that while physics and chemistry 
            had well described "natural laws" no one had truly outlined 
            a verifiable set of fundamental laws (or principles) of biology. At 
            the time it caused a bit of a stir, because the idea seemed to crystallize 
            the differences between the ecologists who wanted to look holistically 
            at complex (chaotic?) systems and the molecular biologists who wanted 
            to determine the nature of the life by determining gene function. 
            Stuck somewhere in the middle were several ideas which all could agree 
            contained some element of fact, but which were discounted because 
            they did not follow the paradigms of either camp. I offer them here 
            as a starting point for discussion on the key insights of biology 
            which Todd would like to identify.
 Definitions:
 1. Unit life is composed of delimited, self-assembing/replicating 
            systems that reorganize matter and energy at the molecular level.
 2. Life systems are agglomerations of unit life forms and have emergent 
            properties.
 3. Evolution is the change of life systems over time, while mutation 
            is the change of unit life.
 Principles:
 1. Changes in life systems follow from stochastic mutations in unit 
            life.
 2. Life is subject to constraints at both the unit and system levels.
 3. Increases in complexity of units and systems require concominant 
            increases in matter and energy.
 4. Complexity increases with time within the constraints imposed over 
            time.
 While the buzz words of modern biology (ecosystems, Darwinism, genomics, 
            etc) are absent, the concepts are embedded in this framework. And, 
            unlike the misapplication of those lesser (?) ideas to human societies, 
            the above principles lead to rather humbling but exciting predictions 
            about the life system known as humanity. And isn't that a fundamental 
            driving force in our search for knowledge? I would welcom any comments 
            and criticisms on this framework, and I would challenge someone to 
            restructure the fundamentals / key insights from other disciplines 
            into a parallel framework.
 Dr. Brian McSpadden Gardener
 USDA-ARS Root Disease and Biological Control Unit
 Washington State University
 Pullman, WA 99164
 (509) 335 1116
 (509) 335 7674 FAX
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