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When I was a first-year
graduate student (some time ago), I had the opprotunity to learn how
to use a slide maker and proceeded to develop a brief seminar for
friends about FuPoBs (Fundamental Principles of Biology). At the time,
I was (mistakenly?) under the impression that while physics and chemistry
had well described "natural laws" no one had truly outlined
a verifiable set of fundamental laws (or principles) of biology. At
the time it caused a bit of a stir, because the idea seemed to crystallize
the differences between the ecologists who wanted to look holistically
at complex (chaotic?) systems and the molecular biologists who wanted
to determine the nature of the life by determining gene function.
Stuck somewhere in the middle were several ideas which all could agree
contained some element of fact, but which were discounted because
they did not follow the paradigms of either camp. I offer them here
as a starting point for discussion on the key insights of biology
which Todd would like to identify.
Definitions:
1. Unit life is composed of delimited, self-assembing/replicating
systems that reorganize matter and energy at the molecular level.
2. Life systems are agglomerations of unit life forms and have emergent
properties.
3. Evolution is the change of life systems over time, while mutation
is the change of unit life.
Principles:
1. Changes in life systems follow from stochastic mutations in unit
life.
2. Life is subject to constraints at both the unit and system levels.
3. Increases in complexity of units and systems require concominant
increases in matter and energy.
4. Complexity increases with time within the constraints imposed over
time.
While the buzz words of modern biology (ecosystems, Darwinism, genomics,
etc) are absent, the concepts are embedded in this framework. And,
unlike the misapplication of those lesser (?) ideas to human societies,
the above principles lead to rather humbling but exciting predictions
about the life system known as humanity. And isn't that a fundamental
driving force in our search for knowledge? I would welcom any comments
and criticisms on this framework, and I would challenge someone to
restructure the fundamentals / key insights from other disciplines
into a parallel framework.
Dr. Brian McSpadden Gardener
USDA-ARS Root Disease and Biological Control Unit
Washington State University
Pullman, WA 99164
(509) 335 1116
(509) 335 7674 FAX |